Sophanna Lout
About Sophanna Lout
Sophanna Lout is a Manufacturing Compliance Manager at Wave Life Sciences, specializing in the Ultrafiltration and Diafiltration process. With a background in biology and extensive experience in manufacturing and quality assurance, Lout contributes to compliance and training initiatives in biopharmaceutical production.
Work at Wave Life Sciences
Sophanna Lout has held the position of Manufacturing Compliance Manager at Wave Life Sciences since 2018. In this role, she oversees compliance within manufacturing processes, ensuring adherence to safety and environmental standards. Her responsibilities include assisting with the execution of Environmental Test Protocols (ETPs) and conducting smoke studies. Lout serves as a Subject Matter Expert (SME) on the Ultrafiltration and Diafiltration (UFDF) process, contributing to the precision and reliability of manufacturing operations.
Education and Expertise
Sophanna Lout studied at Emmanuel College in Boston, where she earned a Bachelor of Science (B.S.) degree in Biology/Biological Sciences from 2006 to 2008. Her educational background provides a solid foundation for her expertise in manufacturing compliance and biopharmaceutical processes. Lout is certified as a visual inspector and trainer, enhancing quality assurance and training programs within her field.
Background in Biopharmaceutical Manufacturing
Lout has extensive experience in biopharmaceutical manufacturing, having worked in various roles across multiple organizations. Prior to her current position, she served as a Senior Manufacturing Associate at Amgen from 2014 to 2018, where she performed upstream and downstream processes. She also worked at Genzyme and MassBiologics, gaining valuable experience in manufacturing operations. Her involvement in the launch of Imlygic, the first oncolytic virus therapy approved by the FDA, highlights her contributions to significant projects in the industry.
Previous Work Experience
Before her tenure at Wave Life Sciences, Sophanna Lout held several positions that contributed to her expertise in the field. She worked as a Lab Technician at Abcam for two months in 2008 and as a Research Assistant at Beth Israel Deaconess Medical Center from 2008 to 2009. Additionally, she served as a Senior Manufacturing Associate at Genzyme from 2012 to 2014 and as a Manufacturing Associate at MassBiologics from 2009 to 2012. This diverse experience has equipped her with a comprehensive understanding of biopharmaceutical manufacturing processes.
Technical Contributions
In her role as Manufacturing Compliance Manager, Sophanna Lout has made significant technical contributions to manufacturing processes. She has characterized crimpers on fillers, enhancing the precision and reliability of manufacturing operations. Lout's expertise extends to performing multiple upstream and downstream processes, including cell expansions and aseptic interventions in Restricted Access Barrier Systems (RABS) and Biological Safety Cabinets (BSC). Her involvement in the first commercial and clinical fill of T-VEC further demonstrates her capability in handling complex biopharmaceutical products.