Sebastien Igonet

Senior Scientist @ AbCellera

About Sebastien Igonet

Sebastien Igonet is a Senior Scientist currently working at AbCellera in Vancouver, Canada, with extensive experience in bioproduction and structural biology. He has a PhD in Structural Immunology and has contributed significantly to the field through his work at various prestigious institutions, including CALIXAR and the Institut Pasteur.

Current Role at AbCellera

Sebastien Igonet serves as a Senior Scientist at AbCellera, a position he has held since 2020. In this role, he applies his expertise in biochemistry and structural biology to advance the company's research initiatives. His work focuses on the development of therapeutic antibodies and other biologics, leveraging his extensive background in protein biochemistry and molecular modeling.

Previous Experience at CALIXAR

Prior to joining AbCellera, Sebastien Igonet worked at CALIXAR as a Senior Scientist specializing in Membrane Protein Biochemistry from 2013 to 2020. During his seven years at CALIXAR, he contributed to the understanding and manipulation of membrane proteins, enhancing the company's capabilities in bioproduction and structural analysis.

Education and Expertise

Sebastien Igonet earned his Doctor of Philosophy (PhD) in Structural Immunology from the Pasteur Institute, where he also completed a Master's degree in Biochemistry. His academic background includes studies in Biochemistry and Structural Biology at Université Paris Diderot. He possesses advanced skills in various biophysical techniques and has deposited 19 atomic structures in the Protein Data Bank (PDB), demonstrating his expertise in structural biology.

Research Background

Sebastien Igonet has a diverse research background, having worked at notable institutions such as the Institut Pasteur and The Scripps Research Institute. At the Institut Pasteur, he held roles as a PhD student and later as a Research Associate from 2002 to 2010. He then transitioned to The Scripps Research Institute, where he served as a Senior Research Associate from 2010 to 2013, focusing on protein structure and function.

Technical Skills and Specializations

Sebastien Igonet is proficient in various biotechnological techniques, including ligand binding assays, electron microscopy, and protein crystallization methods. He specializes in the overexpression of proteins in different cell systems, particularly insect cells. His skills extend to protein stabilization techniques and the use of robotic systems for high-throughput crystallization, contributing to drug discovery and development efforts.

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