Carisma Therapeutics

Carisma Therapeutics is a biotechnology company based in Philadelphia, specializing in the development of CAR-Macrophage and CAR-Monocyte technologies for cancer treatment, with a focus on solid tumors.

Overview of Carisma Therapeutics

Carisma Therapeutics is at the forefront of innovative cancer treatment technologies, specifically focusing on CAR-Macrophage and CAR-Monocyte technologies. The company is pioneering the development of CAR-Macrophages, an advanced form of immunotherapy aimed at targeting solid tumors. Headquartered in Philadelphia, PA, Carisma Therapeutics is engaged in both clinical studies and strategic partnerships to advance the adoption of its technologies.

CAR-Macrophage Technology

Carisma Therapeutics specializes in the development of CAR-Macrophage technology, a groundbreaking approach in the field of immunotherapy. This technology harnesses the power of engineered macrophages to engage both the innate and adaptive immune systems to attack cancerous tumors. Unlike traditional therapies, CAR-Macrophages are designed to sustain their anti-tumor phenotype even under immunosuppressive conditions, providing a resilient approach to combat solid tumors.

CAR-Monocyte Innovations

In addition to CAR-Macrophages, Carisma Therapeutics is advancing CAR-Monocyte technologies for cancer treatment. These engineered monocytes are part of the company's pipeline aimed at providing targeted therapeutic options for cancer patients. Both CAR-Macrophage and CAR-Monocyte technologies are under active clinical studies, positioning Carisma Therapeutics as a leader in next-generation cancer immunotherapy.

Partnership with Moderna Therapeutics

Carisma Therapeutics has partnered with Moderna Therapeutics to develop macrophage-targeted in vivo therapies. This collaboration leverages Moderna's expertise in mRNA technology and Carisma's pioneering work in macrophage engineering to create innovative treatments aimed at enhancing the body's immune response to cancer.

Philadelphia Business Journal Recognition

Carisma Therapeutics has received recognition from the Philadelphia Business Journal as one of the 2023 Best Places to Work. This accolade reflects the company's commitment to creating a supportive and dynamic work environment for its employees while advancing groundbreaking medical treatments.

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