Cisterna Biologics
Cisterna Biologics, based in San Diego, California, specializes in developing mRNA-based therapeutics, focusing on improving quality, quantity, longevity, and cost.
Company Overview
Founded in 2022 and based in San Diego, California, Cisterna Biologics operates in the healthcare industry with a specialized focus on synthetic biology, biotechnology, and therapeutics. The company aims to address significant challenges in the biotech industry concerning the development of mRNA-based therapeutics. Currently at the early stage of development, Cisterna Biologics is part of the Y Combinator (YC) batch S22 and serves regions in the United States of America and America/Canada.
Technologies and Innovations
Cisterna Biologics employs proprietary technologies to improve the quality, quantity, longevity, and cost-effectiveness of mRNA production. One notable technology includes the use of ribozymes to cut mRNA at its 3’ end, promoting 3’ homogeneity and eliminating double-stranded RNA (dsRNA). Additionally, the company utilizes a PCR-like system to amplify DNA templates in large quantities, thereby avoiding plasmid enrichment in bacteria. These innovations aim to achieve mRNA of 10 times higher quality for therapeutic applications.
Focus Areas
Cisterna Biologics concentrates on several key areas within the biotech industry. The company focuses on the development of mRNA-based therapeutics, addressing critical factors such as quality, quantity, longevity, and cost. Additionally, Cisterna Biologics prioritizes the removal of contaminants or the replacement of the source in the mRNA production process, utilizing advanced technologies to enhance the overall outcomes.
Location and Team
Headquartered in San Diego, California, Cisterna Biologics maintains an active status and operates with a small team of 2 members. The company focuses on serving regions within the United States of America and America/Canada. Despite its modest size, Cisterna Biologics is making significant strides in the healthcare sub-industry of synthetic biology, biotech, and therapeutics.
Y Combinator Involvement
Cisterna Biologics is a participant in the Y Combinator (YC) batch S22, which provides the company with resources and mentorship as it navigates the early stages of development. This involvement is a testament to Cisterna Biologics' potential impact on the healthcare and biotech industries, particularly in the realm of mRNA-based therapeutic development.