Cogent Biosciences

Cogent Biosciences, based in Waltham, Massachusetts and Boulder, Colorado, specializes in developing precision therapies for genetically defined diseases, with a focus on bezuclastinib for systemic mastocytosis and gastrointestinal stromal tumors.

Company Locations

Cogent Biosciences operates two main offices located in Waltham, Massachusetts, and Boulder, Colorado. These locations enable the company to leverage the robust biotech and pharmaceutical ecosystems prevalent in these regions. The geographical diversification supports their cutting-edge research and development activities in creating precision therapies for genetically defined diseases.

Precision Therapy Development

Cogent Biosciences specializes in the development of precision therapies aimed at genetically defined diseases. Their approach centers on the rational design of therapies that target the underlying causes of diseases, moving away from symptomatic treatment methods. This innovative strategy focuses on addressing genetic and molecular defects directly, leading to more effective and targeted treatment solutions.

Clinical Pipeline and Bezuclastinib

The clinical pipeline of Cogent Biosciences is primarily centered around bezuclastinib, a selective and potent KIT inhibitor. Bezuclastinib is in late-stage development for the treatment of Advanced and Nonadvanced Systemic Mastocytosis and Gastrointestinal Stromal Tumors. This focus underscores the company's commitment to developing targeted therapies that can rapidly progress through clinical phases, addressed to well-characterized disease biology.

Research and Preclinical Assets

Cogent Biosciences is deeply invested in research to advance its preclinical assets. The company targets diseases with genetically defined characteristics and well-characterized biology to ensure a clear path from discovery to development. This strategic focus allows for rapid advancement through the development pipeline, aiming to deliver specialized therapies effectively to patients in need.

Focus on Genetically Defined Diseases

Cogent Biosciences dedicates its resources to targeting genetically defined diseases. The emphasis on well-characterized biological mechanisms enables the company to design and develop therapies with precision. This focused approach accelerates the development timeline and enhances the likelihood of clinical success, positioning the company at the forefront of next-generation therapeutic development.

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