Junguo (Joe) Zhou, PhD, Dabt
About Junguo (Joe) Zhou, PhD, Dabt
Junguo (Joe) Zhou, PhD, Dabt, serves as the Executive Director and Head of Toxicology at Insmed Incorporated, where he oversees toxicology support for various therapeutic portfolios. With extensive experience in nonclinical safety, he has held significant roles at prominent organizations, including The Janssen Pharmaceutical Companies of Johnson & Johnson and Bayer CropScience.
Work at Insmed
Junguo (Joe) Zhou serves as the Executive Director and Head of Toxicology at Insmed Incorporated. In this role, he oversees toxicology support for a diverse portfolio that includes small molecules, protein therapeutics, and gene therapies. His responsibilities include leading nonclinical safety assessments for active pharmaceutical ingredients (APIs), leachables, extractables, and impurities. He has been with Insmed since 2021, contributing to the company's focus on developing innovative therapies.
Previous Experience at Janssen Pharmaceutical
Prior to his current role, Zhou worked at The Janssen Pharmaceutical Companies of Johnson & Johnson from 2015 to 2021. He held various positions, including Principal Scientist, Scientific Director, and Senior Principal Scientist. His responsibilities included leading nonclinical safety assessments, overseeing US nonclinical submissions, and representing the toxicology department in project team meetings. He contributed to both in-licensing and out-licensing opportunities during his tenure.
Education and Expertise
Zhou holds a Doctor of Philosophy (Ph.D.) in Toxicology from the University of Rochester School of Medicine and Dentistry. He also completed a post-doctoral fellowship at the National Institute of Environmental Health Sciences (NIEHS) in the Laboratory of Signal Transduction. His academic background includes a Master of Science (M.S.) in Medicinal Chemistry from the Chinese Academy of Medical Sciences and Peking Union Medical College, and a Bachelor of Science (B.S.) in Medicinal Chemistry from West China University of Medical Sciences.
Background in Toxicology
Zhou has extensive experience in toxicology, having worked in various capacities since 2003. His career includes positions at the National Institute of Environmental Health Sciences as a Postdoctoral Researcher and at Bayer CropScience as a Senior Scientist in Regulatory Toxicology. His expertise encompasses conducting occupational and environmental risk assessments for APIs, as well as authoring and reviewing nonclinical safety modules in regulatory documents.