Yue Yang

About Yue Yang

Yue Yang is a Staff Scientist at Lawrence Livermore National Laboratory, where he leads oncology drug discovery projects and GTPase stimulator discovery projects. He has a background in computational chemistry and has held various research positions, including a role as a Computational Chemist at ATOM and a Postdoc Fellow at Lawrence Livermore.

Current Role at Lawrence Livermore National Laboratory

Yue Yang currently serves as a Staff Scientist at Lawrence Livermore National Laboratory, a position held since 2015. In this role, Yang focuses on various aspects of drug discovery, particularly in oncology. Yang leads projects aimed at discovering GTPase stimulators and KRas inhibitors, collaborating with industry partners to advance these initiatives. The research also includes the study of hERG induced cardiotoxicity, contributing to the understanding of drug safety profiles.

Previous Experience at ATOM

Prior to the current position, Yue Yang worked as a Computational Chemist at ATOM | Accelerating Therapeutics for Opportunities in Medicine from 2017 to 2018. During this 11-month tenure in the San Francisco Bay Area, Yang contributed to computational approaches in drug discovery, enhancing the understanding of therapeutic opportunities through advanced computational methods.

Postdoctoral Fellowship at Lawrence Livermore National Laboratory

Yue Yang completed a Postdoctoral Fellowship at Lawrence Livermore National Laboratory from 2012 to 2015. This three-year period involved extensive research in the field of chemical physics, further developing expertise in protein engineering and drug discovery methodologies.

Educational Background in Chemical Physics

Yue Yang earned a Bachelor of Science degree in Chemical Physics from the University of Science and Technology of China, studying from 1998 to 2003. Later, Yang pursued a PhD in Computational Chemistry at the University of Florida, completing the program from 2006 to 2011. This educational foundation provided a strong basis for Yang's research and professional endeavors in the field of chemistry.

Research Contributions and Projects

Throughout the career, Yue Yang has been involved in significant research projects, including protein engineering on phosphoenolpyruvate carboxykinase for non-native ligand binding. Yang has also conducted research on Ras-lipid association, contributing to the understanding of molecular interactions relevant to drug discovery and development.

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