James A. Coffman

Associate Professor @ MDI Biological Laboratory

About James A. Coffman

James A. Coffman: Associate Professor

James A. Coffman holds the position of Associate Professor. His academic focus includes studying the effects of environmental factors on health, particularly within the realm of biomedical research. In addition to his teaching responsibilities, Coffman is heavily involved in research aimed at understanding intricate biological processes.

Director of Maine IDeA Network of Biomedical Research Excellence (INBRE)

James A. Coffman serves as the Director of the Maine IDeA Network of Biomedical Research Excellence (INBRE). Under his leadership, the network aims to enhance biomedical research infrastructure and training. The INBRE program is designed to build capacity and infrastructure in the biomedical research field across Maine, and Coffman plays a pivotal role in advancing these objectives.

Arsenic Exposure and Depression Research Grant

James A. Coffman was awarded a $449,000 grant for his research on the potential link between arsenic exposure and depression. The research uses zebrafish as a model to investigate these effects. This significant grant supports Coffman's commitment to exploring the impact of environmental toxins on mental health.

Collaborations with Leading Researchers

James A. Coffman collaborates with Michael Burman, Ph.D., from the University of New England, and Erik Duboué, Ph.D., from Florida Atlantic University on research focused on arsenic exposure. This multidisciplinary partnership aims to dissect the biological mechanisms that underlie the observed effects of early-life arsenic exposure on brain development and behavior.

Impact of Arsenic on Brain Development and Behavior

James A. Coffman's research places specific emphasis on understanding how early-life arsenic exposure affects brain development and behavior using zebrafish models. He investigates disruptions in glucocorticoid receptor signaling and markers of inflammation in the brain. This research is crucial in identifying potential pathways through which arsenic may contribute to neurodevelopmental and behavioral disorders.

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