William (Bill) Dowdle, PhD
About William (Bill) Dowdle, PhD
William (Bill) Dowdle, PhD, is the Senior Director of Genome Modification at Sana Biotechnology, Inc., where he has worked since 2021. He has extensive experience in genome editing and drug target validation, having previously held positions at notable institutions including Harvard Medical School, UCSF, and Novartis.
Current Role at Sana Biotechnology
William Dowdle serves as the Senior Director of Genome Modification at Sana Biotechnology, Inc. since 2021. In this role, he leads multidisciplinary project teams focused on the progression of drug candidates. His expertise in CRISPR genome editing is instrumental in probing signaling pathways that regulate protein turnover. Dowdle's leadership in genome modification is crucial for the company's mission to develop transformative therapies.
Previous Experience in Biotechnology
Before his current position, William Dowdle held several significant roles in the biotechnology field. He was a Principal Scientist at Sana Biotechnology, Inc. from 2019 to 2020 and served as a Senior Scientist at Maze Therapeutics for six months in 2018. Additionally, he worked as a Senior Scientist and Pathway Leader at Denali Therapeutics in 2018 and as a Postdoctoral Fellow at Novartis from 2012 to 2015. His diverse experience spans various aspects of drug development and research.
Education and Expertise
William Dowdle earned his Ph.D. in Developmental Biology from the University of California, San Francisco, where he studied from 2006 to 2012. He also holds a Bachelor of Science in Biotechnology from the Rochester Institute of Technology, completed from 2000 to 2004. His educational background provides a strong foundation in mouse genetics, chemical genetics, proteomics, biochemistry, and imaging, contributing to his expertise in drug target identification and validation.
Research Experience at Harvard Medical School and UCSF
William Dowdle began his research career as a Research Assistant at Harvard Medical School from 2004 to 2006. He then continued his academic journey as a PhD Candidate at UCSF from 2006 to 2012. This early experience in prestigious institutions laid the groundwork for his subsequent roles in the biotechnology industry, enhancing his skills in research and development.
Skills and Contributions
William Dowdle possesses excellent communication skills, enabling him to present complex information to diverse audiences effectively. His demonstrated ability to identify and validate drug targets in preclinical research is a significant asset in his field. Dowdle's strong background in various scientific disciplines allows him to contribute meaningfully to the advancement of therapeutic candidates.