Reyal Hoxie
About Reyal Hoxie
Reyal Hoxie is a Scientist I at 1910 Genetics, specializing in Translational Biochemistry & Pharmacology, where she focuses on automating assay development for high throughput screening of therapeutics.
Reyal Hoxie Scientist I Role
Reyal Hoxie holds the position of Scientist I in Translational Biochemistry & Pharmacology at 1910 Genetics. In her role, she leverages state-of-the-art robotics to automate the development, validation, and scale-up of assay processes. These automated assays are central to the high throughput screening of therapeutics designed by the AI-powered ELVIS™ and ROSALYND™ platforms. Her expertise in biochemistry and pharmacology enables her to contribute significantly to the advancements in the field of translational research.
Reyal Hoxie Education
Reyal Hoxie earned her Ph.D. in Biochemistry and Biophysics from Brandeis University. During her doctoral studies, she investigated the energetics of binding for Hsp90 inhibitors. Additionally, she examined how these inhibitors affect the role of BiP on Grp94 conformation. Her research added valuable insights into the mechanistic underpinnings of molecular chaperone interactions.
Biological Automation at 1910 Genetics
At 1910 Genetics, Reyal Hoxie works on all aspects of the biological automation platform. This includes tasks from the design and operation of automated systems to the implementation of assays for high throughput screening. Her work aims to boost efficiency and accuracy, thus accelerating the discovery and validation of new therapeutics. She ensures that the robotic systems are optimized for scale-up processes, aiding in the rapid progression from initial discovery stages to clinical testing.
Reyal Hoxie Ph.D. Research
During her Ph.D. at Brandeis University, Reyal Hoxie conducted detailed research on the energetics of binding for Hsp90 inhibitors. Additionally, she explored how Hsp90 inhibitors alter the effects of BiP on the conformation of Grp94. This research was critical in understanding the molecular mechanisms that underlie these protein interactions, potentially influencing the development of targeted therapeutic strategies.