Fen Zhang
About Fen Zhang
Fen Zhang is a Director at Abalone Bio, specializing in antibody development and optimization. With advanced degrees in Biophysics, Cell Biology, and Physics, he has co-invented bispecific technologies and successfully humanized numerous antibody candidates.
Work at Abalone Bio
Fen Zhang serves as the Director at Abalone Bio, where he focuses on antibody development and optimization. His role complements the team's expertise in protein work and yeast, contributing to the advancement of biotherapeutics. Since joining the company in 2019, he has played a significant part in enhancing the capabilities of the organization in the field of antibody research.
Education and Expertise
Fen Zhang holds a Master of Science in Biophysics from Tsinghua University, where he studied from 1982 to 1985. He furthered his education with a PhD in Cell Biology and Anatomy from the University of North Carolina at Chapel Hill, attending from 1986 to 1992. Additionally, he earned a Bachelor of Science in Physics and Electronics from Peking University, studying from 1978 to 1982. His educational background provides a strong foundation for his work in antibody development.
Background
Fen Zhang has a diverse academic and professional background in the life sciences. His early education in Physics and Electronics laid the groundwork for his later studies in Biophysics and Cell Biology. This multidisciplinary approach has informed his work in antibody technology and therapeutic development, enabling him to contribute effectively to the biopharmaceutical industry.
Achievements
Fen Zhang co-invented two bispecific technologies, with one technology progressing to human clinical trials. He has successfully humanized over ten murine antibody therapeutic candidates and has invented or improved four different single B cell molecular cloning techniques. Additionally, he generated approximately 30 CHO cell lines that produce antibodies exceeding 1 g/L, with one of these lines being adopted for manufacturing purposes.