Lane Jaeckle Santos, PhD, Rac
About Lane Jaeckle Santos, PhD, Rac
Lane Jaeckle Santos, PhD, is the Associate Director of CMC Submissions at Adaptimmune in Philadelphia, Pennsylvania. She has extensive experience in regulatory affairs and drug development, with a focus on antibody-based therapeutics and biologics.
Current Role at Adaptimmune
Lane Jaeckle Santos serves as the Associate Director of CMC Submissions at Adaptimmune, a position she has held since 2021. In this role, she is responsible for overseeing the regulatory submissions related to Chemistry, Manufacturing, and Controls (CMC). Her expertise in this area is crucial for ensuring compliance with regulatory standards and facilitating the development of new therapeutics.
Previous Experience in Regulatory Affairs
Before her current role, Santos worked at Adaptimmune as Principal Scientist in CMC Regulatory Submissions from 2018 to 2021. She also held the position of CMC Regulatory, Manufacturing Science & Technology from 2017 to 2018. Her experience includes authoring and editing regulatory documents that support new drug applications (NDAs) and investigational new drug (IND) applications across various therapeutic areas.
Educational Background
Santos earned her PhD in Integrative Biology, Human Genetics, and Genomics from The University of Texas Southwestern Medical Center at Dallas, where she studied from 2003 to 2009. She also completed a certificate program in Regulatory Affairs for the Biomedical Industry at the University of California, San Diego, from 2014 to 2016. Additionally, she holds a Bachelor of Science degree in Biology with a minor in Chemistry from St. Mary's University, obtained from 1998 to 2002.
Research and Scientific Contributions
Santos has over 10 years of preclinical research experience, particularly in inflammation, metabolism, and Type 2 Diabetes pathophysiology. Her work has involved authoring various regulatory documents, including clinical study reports, safety update reports, and clinical trial disclosures. She has also delivered over 20 presentations at national and international conferences, demonstrating her expertise and communication skills in the field.
Professional Experience in Academia and Industry
Prior to her roles at Adaptimmune, Santos worked at The Children's Hospital of Philadelphia as a Research Scientist I for eight months in 2015-2016. She also served as a Postdoctoral Fellow at the University of Pennsylvania from 2009 to 2014 and held the position of Senior Research Scientist II at the same institution from 2014 to 2016. Her diverse experience spans both academic and industry settings, contributing to her comprehensive understanding of drug development.