Yuan Hu
About Yuan Hu
Yuan Hu is an Associate Principal Scientist at Alkermes with extensive experience in computational chemistry and drug discovery.
Title and Current Role
Yuan Hu is currently an Associate Principal Scientist at Alkermes. In this role, Yuan contributes to advancing scientific research and development within the company.
Previous Experience at Alkermes
Yuan Hu has held several positions at Alkermes, including Senior Scientist from 2019 to 2021 and Scientist from 2017 to 2021. During these years, Yuan worked on various scientific projects and contributed to the company's research initiatives based in Waltham, MA.
Past Roles at Merck and University of Delaware
Before joining Alkermes, Yuan Hu worked at Merck as an Associate Research Scientist from 2015 to 2017. Yuan also gained extensive experience at the University of Delaware as a Teaching and Research Assistant from 2010 to 2015 while pursuing a Ph.D.
Educational Background and Research Specialization
Yuan Hu holds a Ph.D. in Organic Catalysis and Computational Chemistry from the University of Delaware, earned in 2015. Yuan also obtained a Master of Science degree in Organic Chemistry in 2010 and a Bachelor of Science degree in Chemistry in 2008, both from Wuhan University. During the Ph.D. program, Yuan's research focused on molecular dynamics simulation methods for understanding cellular mechanisms.
Collaborative and Technical Contributions
Yuan Hu collaborated with Professor Darrin York's group at Rutgers University to develop Amber GPU TI code, enhancing computational chemistry capabilities. At Merck, Yuan worked on developing free energy workflows to improve protein-ligand affinity prediction in drug discovery. Yuan is proficient in various free energy calculation techniques, including MMGBSA, MMPBSA, LIE, FEP, TI, and Lambda-Dynamics.