Caroline Kӧhrer
About Caroline Kӧhrer
Caroline Kӧhrer VP Discovery Platform
Caroline Kӧhrer holds the title of VP, Discovery Platform, bringing over 25 years of experience in both academic and industrial research and development. Her notable roles have included Director of RNA Science at Moderna, where she led the RNA Science Department within Moderna's R&D Platform. In her current capacity, she continues to leverage her extensive expertise to advance innovative solutions in drug development and RNA science.
Caroline Kӧhrer's Education and Expertise
Caroline Kӧhrer earned her M.S. and Ph.D. in microbiology from the University of Innsbruck, Austria. Her expertise spans a variety of scientific disciplines, including RNA science, protein synthesis, and mRNA therapeutics. Throughout her career, she has focused on the role of transfer RNA (tRNA), RNA modifications in translation, rules of mRNA decoding, genetic code expansion, and ribosome biogenesis.
Caroline Kӧhrer's Background in Research and Development
Caroline Kӧhrer has dedicated over 25 years to both academic and industrial research and development. She spent 20 years at the Massachusetts Institute of Technology, performing research focused on protein synthesis across all kingdoms of life. Within the industrial sector, she has played a crucial role at Moderna, particularly in developing mRNA-based technology for applications in infectious diseases, oncology, and personalized cancer medicine.
Caroline Kӧhrer's Contributions to mRNA Therapeutics
At Moderna, Caroline Kӧhrer contributed significantly to expanding the mechanistic understanding of mRNA design principles. Her work has been pivotal in the development of current and future mRNA therapeutics, including Moderna's Spikevax mRNA vaccine for COVID-19. She has developed mRNA-based technologies applicable to infectious diseases, personalized cancer medicine, oncology, autoimmune disorders, and rare diseases.
Caroline Kӧhrer's Publications and Editorial Contributions
Caroline Kӧhrer has co-authored more than 40 publications, book chapters, and patents. Her peer-reviewed work has appeared in journals such as PNAS, Nature Communications, Cell Metabolism, and Nucleic Acid Therapeutics. She also co-edited a book on 'Protein Engineering' published by Springer and contributed a chapter on 'Specialized Components of the Translational Machinery for Unnatural Amino Acid Mutagenesis.'