Yujie Zhang
About Yujie Zhang
Yujie Zhang is the Analytical Director at BeiGene with over 8 years of experience in the biopharmaceutical industry, specializing in antibody-based drug programs and structural biology.
Current Role at BeiGene
Yujie Zhang currently holds the position of Analytical Director at BeiGene. In this role, Yujie is responsible for overseeing analytical processes and ensuring compliance with Good Manufacturing Practices (GMP) in the development of recombinant biologics. His role encompasses the entire spectrum from cell line development to Phase III clinical trials, ensuring accuracy and efficacy in drug development.
Previous Experience at Zhejiang Teruisi Pharmaceutical Inc.
Yujie Zhang previously held several positions at Zhejiang Teruisi Pharmaceutical Inc. From 2018 to 2020, he served as the Senior Director, contributing his expertise in biopharmaceuticals. Before that, from 2016 to 2018, he was the Director. His tenure at the company began in 2013 when he started as an Associate Director/Senior Scientist. Over these years, he played a significant role in the development and quality control of antibody drug conjugates, focusing on conjugation process control, DAR value process control, and ADC products lot release and characterization.
Educational Background
Yujie Zhang earned his Ph.D. in Structural Biology from 中国科学技术大学, where he studied from 2008 to 2013. His doctoral research equipped him with a deep understanding of structural biology and protein chemistry. Prior to this, he obtained a Bachelor’s degree in Biological Sciences from 安徽大学, which he attended from 2004 to 2008. His academic background provided a strong foundation in molecular biology, including techniques like PCR and qPCR, vector construction, and protein engineering.
Experience in Biopharmaceutical Industry
With over 8 years of experience in the biopharmaceutical industry, Yujie Zhang has a comprehensive understanding of the field. He has been involved in the successful development of over 10 antibody-based drug programs focusing on oncology therapeutics. His broad expertise includes developing physicochemical and bioanalytical assays for in-process testing, lot release, and characterization at the CMC stage. His work ensures that drug development processes adhere to stringent quality and accuracy standards.
Skills in Structural Biology and Protein Chemistry
Yujie Zhang possesses specialized skills in structural biology and protein chemistry. His technical expertise includes protein expression and purification, protein X-ray crystallography, X-ray diffraction data collection on synchrotron radiation beamline or in-house Cu Kα, structure determination, model refinement, and 3-D structure model analysis. This skill set enables him to contribute significantly to the understanding and development of protein-based therapeutics.