William Mallet
About William Mallet
William Mallet is the Senior Director of Target Validation at Bolt Biotherapeutics, Inc., where he has worked since 2022. He has extensive experience in drug discovery, particularly in developing therapeutics for oncology and fibrosis, with a background that includes roles at Genentech, Novartis, and Weill Cornell Medical College.
Current Role at Bolt Biotherapeutics
William Mallet serves as the Senior Director of Target Validation at Bolt Biotherapeutics, Inc. since 2022. In this role, he focuses on the validation of therapeutic targets, particularly in the field of oncology. His responsibilities include overseeing projects that align with the company's strategic goals in drug development. Prior to this position, he worked as a Staff Scientist in Target Validation at the same company from 2018 to 2022, where he contributed to the advancement of antibody-drug conjugate (ADC) programs.
Previous Experience at Genentech and Novartis
Before joining Bolt Biotherapeutics, William Mallet worked at Genentech, Inc. as a Scientist from 2002 to 2010. During his tenure, he contributed to various projects in drug discovery. Following his time at Genentech, he held the position of Senior Investigator I at Novartis from 2010 to 2014 in Emeryville, CA. His work at both companies involved significant contributions to the development of therapeutics, particularly in oncology.
Educational Background in Pharmaceutical Chemistry
William Mallet earned his Ph.D. in Pharmaceutical Chemistry from the University of California, San Francisco, where he studied from 1989 to 1996. His educational journey began at the Massachusetts Institute of Technology, where he obtained a Bachelor of Science in Chemistry from 1982 to 1986. His academic training laid the foundation for his expertise in drug discovery and development.
Research Expertise and Skills
William Mallet possesses extensive expertise in developing therapeutics for both fibrosis and cancer. He has experience in mammalian cell biology and protein biochemistry, which are critical for drug discovery processes. His research methods include fluorescence microscopy and recombinant DNA techniques. He is also recognized for his strong skills in team-building and project prioritization, essential for successful drug development.
Postdoctoral and Graduate Research Experience
After completing his Ph.D., William Mallet conducted postdoctoral research at Weill Cornell Medical College from 1996 to 1999. He also gained valuable experience as a graduate student at UCSF from 1989 to 1996. These roles contributed to his development as a scientist and provided him with a solid foundation in research methodologies relevant to pharmaceutical sciences.