Satyakam Singh, Ph.D.
About Satyakam Singh, Ph.D.
Satyakam Singh, Ph.D., is a Sr. Principal Scientist specializing in CAR-T Cell Therapy Analytical Development at Bristol Myers Squibb in the Greater Seattle Area.
Title
Satyakam Singh, Ph.D., currently holds the title of Sr. Principal Scientist, (CAR-T) Cell Therapy Analytical Development at Bristol Myers Squibb in the Greater Seattle Area.
Company
Satyakam Singh, Ph.D., is employed at Bristol Myers Squibb, where he contributes significantly to the field of CAR-T Cell Therapy Analytical Development. Before assuming his current role, he served as Group Lead Scientist in the same department from 2016 to 2019.
Previous Employment
Prior to his tenure at Bristol Myers Squibb, Dr. Satyakam Singh worked at Regeneron Pharmaceuticals, Inc. in Albany, New York, as a Scientist in Assay Development and Validation for one year from 2015 to 2016. Additionally, he served as a Research Scientist in Analytical Research and Development at Amneal Pharmaceuticals, Brook Haven, New York, from 2013 to 2015. His prior experience also includes teaching and research roles at prestigious institutions such as St. John's University, Jubilant Life Sciences Ltd., MIT College of Pharmacy, and Central Drug Research Institute.
Education and Expertise
Dr. Satyakam Singh earned his Doctor of Philosophy (Ph.D.) in Pharmaceutical Sciences with a focus on Medicinal and Pharmaceutical Chemistry from St. John's University, New York, between 2008 and 2013. He also holds a Master of Pharmaceutical Sciences from Shri G S Institute of Technology & Science (2004 to 2006) and a B.S. in Pharmacy from Uttar Pradesh Technical University (2001 to 2004). His educational background is further bolstered by a D.Pharmacy from Govt. Polytechnic Nainital and a Bachelor of Science in Chemistry from the University of Lucknow.
Publications and Research
Throughout his academic and professional career, Dr. Satyakam Singh has authored 28 manuscript publications from his Ph.D. research. These papers have been published in high-impact journals and have collectively accumulated over 1000 citations. His research contributions significantly advance the field of medicinal and pharmaceutical chemistry.
Technical Skills
Dr. Satyakam Singh is proficient in various analytical tools and techniques, including HPLC/UPLC with Empower-3, SEM, Raman Spectroscopy, ICP-MS, Rheometer, LC-MS, FT-IR micro-spectroscopy, XRD, DSC, TGA, GC-MS, 1D/2D-NMR, and Particle Size Analysis by Micro-Flow Imaging and Malvern. He is also skilled in using Laboratory Information Management Systems (LIMS) and JMP software, and he is an expert in Computer-Aided Drug Design (CADD) using Schrodinger and Sybyl software.
Regulatory and Process Development
In his current role, Dr. Satyakam Singh leads analytical method development, qualification, and troubleshooting for critical reagents, formulations, and automated process improvements in CAR-T manufacturing. He develops UPLC-based chromatographic methods and plate-based ELISA methods for the biophysical characterization of reagents, cells, and vectors. Additionally, he writes protocols, methods, and reports, and manages their execution, ensuring the successful transfer of methods across sites to support regulatory filings for CAR-T products.