Shyam Karki
About Shyam Karki
Shyam Karki is the Senior Director of Drug Product Development at Bristol-Myers Squibb, with extensive experience in pharmaceutical science and formulation development.
Company
Shyam Karki is currently employed at Bristol-Myers Squibb as the Senior Director of Drug Product Development in Summit, New Jersey. Since joining Bristol-Myers Squibb, he has been key in technology transfer processes and has played a significant role in formulation design and development following the acquisition of Celgene.
Title
Shyam Karki holds the position of Senior Director of Drug Product Development at Bristol-Myers Squibb. His role encompasses process development and scale-up, ensuring that the drug products are effectively and efficiently brought from the discovery phase through to product registration.
Education and Expertise
Shyam Karki earned his Ph.D. in Physical Organic Chemistry from the University of Rochester, where he studied from 1989 to 1995. Prior to that, he completed a Bachelor of Science in Chemistry from Davidson College between 1984 and 1988. Karki also achieved a Cambridge O' Level from St. Xavier's School in Kathmandu, Nepal, where he studied from 1973 to 1983. His extensive academic background has provided him with a strong foundation in drug product development.
Career Background
Shyam Karki has nearly three decades of experience in the pharmaceutical industry. Before his current role at Bristol-Myers Squibb, he served as the Senior Director and Head of Pharmaceutical Science and Formulation Development at Celgene from 2016 to 2019. Prior to that, Karki was the Director and Head of Small Molecule Drug Product Development at Biogen from 2012 to 2016. He has also held significant roles at Johnson & Johnson, including Principal Scientist of Biologics Drug Product Development from 2010 to 2012 and Director and Head of Pharmaceutical Science from 2005 to 2010. His earlier career includes positions at Merck, Rohm and Haas, and as a Post Doctoral Fellow at the NSF Center for Photo-Induced Charge Transfer.
Achievements
Throughout his career, Shyam Karki has led teams specializing in pharmaceutical science and formulation development. His expertise spans both small molecule and biologics drug product development. At Bristol-Myers Squibb, he has been instrumental in the technology transfer process and has successfully contributed to formulation design and development. His comprehensive understanding of regulatory requirements ensures that drug products meet all necessary standards for product registration.