J. Michael Krill Burger
About J. Michael Krill Burger
J. Michael Krill Burger is a Computational Scientist I at the Broad Institute of MIT and Harvard, where he has worked since 2014. He has a background in computational biology and has contributed to significant cancer research projects, including the Cancer Dependency Map.
Work at Broad Institute
J. Michael Krill Burger has been employed at the Broad Institute of MIT and Harvard since 2014, serving as a Computational Scientist I. In this role, he contributes to various projects that leverage computational methods to advance cancer research. His work includes the development of analytical tools and pipelines that support the oncology community in identifying potential drug targets and understanding the mechanisms of action for various treatments.
Previous Experience
Before joining the Broad Institute, J. Michael Krill Burger worked at UPMC/UPCI as part of the Cancer Biomarker Facility from 2008 to 2012. His role involved research focused on cancer biomarkers, contributing to the understanding of cancer biology. Additionally, he served as a Teaching Assistant at Carnegie Mellon University for four months in 2014, where he supported the educational development of students in computational biology.
Education and Expertise
J. Michael Krill Burger earned a Master's Degree in Computer Science with a focus on Computational Biology from Carnegie Mellon University, studying from 2012 to 2014. Prior to that, he obtained a Bachelor of Science in Neuroscience from the University of Rochester, completing his studies from 2003 to 2007. His educational background provides a strong foundation in both computational methods and biological sciences.
Research Contributions
In his research, J. Michael Krill Burger has contributed to the Cancer Dependency Map project, utilizing machine learning techniques to identify molecular features that predict sensitivity to gene target inhibition. He has also developed an analysis pipeline for modeling hematologic malignancies using CRISPR genome engineering, which is publicly accessible. His work includes investigating genetic dependencies specific to pediatric cancers as part of collaborative pan-cancer studies.
Focus and Impact
J. Michael Krill Burger focuses on providing the oncology community with insights into potential drug targets that are likely to succeed. His research emphasizes understanding drug mechanisms of action and identifying robust biomarkers, which are critical for advancing cancer treatment strategies and improving patient outcomes.