Jiangchuan (Jc) Ye
About Jiangchuan (Jc) Ye
Jiangchuan (Jc) Ye is a Senior Scientist at Alltrna in Cambridge, Massachusetts, specializing in stem cell and cardiomyocyte research. He has a PhD in Cardiovascular Science and an MD, and has been involved in significant projects related to CRISPR technology and drug target validation.
Work at Alltrna
Jiangchuan Ye has been serving as a Senior Scientist at Alltrna since 2021. He is based in Cambridge, Massachusetts, where he leads a stem cell and cardiomyocyte platform. His work involves generating transgenic cell lines utilizing CRISPR and lentiviral methods. Ye focuses on developing medium-to-high throughput assays for compound or gene-targeting CRISPR screens using differentiated cells.
Work at Broad Institute
Since 2017, Jiangchuan Ye has held the position of Research Scientist II at the Broad Institute of MIT and Harvard in Cambridge, Massachusetts. His research includes performing genome-wide pooled CRISPR screens to investigate the interactome of atrial fibrillation-associated genes. He is also involved in target validation projects aimed at identifying druggable genes for various cardiovascular conditions, including atrial fibrillation, fibrosis, and cardiomyopathy.
Education and Expertise
Jiangchuan Ye earned his Doctor of Medicine (MD) degree from Tongji University, where he studied Medical Clinical Sciences from 2004 to 2009. He further pursued a Doctor of Philosophy (PhD) in Internal Medicine and Cardiovascular Science at the same institution, completing his studies from 2009 to 2012. His educational background provides a strong foundation for his research in cardiovascular health and genetic screening.
Research Focus
Jiangchuan Ye's research primarily centers on the application of CRISPR technology in cardiovascular science. He develops assays for medium-to-high throughput screening and conducts genome-wide pooled CRISPR screens. His work aims to elucidate the genetic factors associated with atrial fibrillation and other cardiovascular diseases, contributing to the understanding of their underlying mechanisms.