Kasper Lage
About Kasper Lage
Kasper Lage serves as the Managing Director of the NNF Center for Genomic Mechanisms of Disease at the Broad Institute, where he leads research on genomic mechanisms of metabolic disorders. He has held various roles in academia and industry, including positions at Biogen, Merck, and Harvard University, and has a strong background in bioinformatics and computational biology.
Work at Broad Institute
Kasper Lage serves as the Managing Director of the NNF Center for Genomic Mechanisms of Disease at the Broad Institute of MIT and Harvard since 2021. In this role, he leads a research center with a budget of approximately 50 million USD, focusing on genomic mechanisms of metabolic disorders. Lage oversees a collaborative effort involving around 200 researchers from the Broad Institute and Denmark. He is also part of the Leadership Group at the Stanley Center for Psychiatric Research at the Broad Institute, a position he has held since 2015.
Education and Expertise
Kasper Lage has a diverse educational background in genetics, bioinformatics, and management. He earned his Ph.D. in Bioinformatics and Systems Biology of Human Diseases from the Technical University of Denmark from 2003 to 2007. He completed postdoctoral research at Harvard University and the Massachusetts Institute of Technology, focusing on Genetics and Computational Biology from 2008 to 2011. Additionally, he obtained an Executive MBA from the MIT Sloan School of Management from 2017 to 2019.
Professional Background
Before his current role, Kasper Lage held various positions in academia and industry. He worked as an Associate Professor at Harvard University from 2017 to 2023 and served as Director of Bioinformatics at the Harvard Reproductive Endocrine Sciences Center from 2008 to 2010. He also contributed to Biogen as a Consultant and Chair of the Genetics and Analytics Advisory Panel from 2016 to 2019, and was a Member of the Advisory Panel in Computational Methods for Target Identification & Validation at Merck from 2017 to 2019.
Research Initiatives
At the NNF Center for Genomic Mechanisms of Disease, Kasper Lage utilizes cutting-edge technologies such as machine learning, single-cell genomics, and quantitative proteomics. His research aims to create a generalizable playbook for addressing complex traits beyond type 2 diabetes and obesity. The center's work is expected to contribute to the development of a new generation of rationally designed medicines.
Collaborative Efforts
Kasper Lage oversees a significant collaborative effort involving around 200 researchers across the Broad Institute and Denmark. This collaboration aims to advance the understanding of genomic mechanisms related to metabolic disorders, leveraging diverse expertise and innovative technologies to drive research outcomes.