Lesley Mathews Griner
About Lesley Mathews Griner
Lesley Mathews Griner serves as the Associate Director of Translational Pharmacology at the Broad Institute of MIT and Harvard, where she has worked since 2021. She has a strong background in oncology research and extensive experience in various laboratory techniques and mentoring.
Work at Broad Institute
Lesley Mathews Griner currently serves as the Associate Director of Translational Pharmacology at the Center for the Development of Therapeutics at the Broad Institute of MIT and Harvard. She has held this position since 2021. Prior to this role, she was the Senior Group Leader in the same center from 2020 to 2021. Her work focuses on advancing therapeutic development through translational pharmacology.
Education and Expertise
Lesley Mathews Griner holds a PhD in Molecular Biology from the University of Massachusetts Amherst, where she studied from 2003 to 2008. She also earned a Master’s Degree in Secondary Education and Teaching in Biology from Lesley University between 2016 and 2020. Additionally, she completed a Post Doctoral Research Fellowship at the National Cancer Institute-NIH, focusing on Cancer Stem Cells from 2008 to 2010. Her academic background supports her specialization in small molecule, antibody drug conjugate, and biologics structure-activity relationship studies.
Professional Background
Lesley Mathews Griner has a diverse professional background in the biomedical research field. She worked as a Principal Scientist II in Oncology Molecular Pharmacology at Novartis Institutes for BioMedical Research from 2017 to 2020. Prior to that, she served as Investigator II in Oncology at Novartis from 2014 to 2017. Her experience also includes roles at the National Center for Advancing Translational Sciences (NCATS)/NIH, where she was a Research Scientist from 2010 to 2014 and a Postdoctoral Research Fellow from 2008 to 2010.
Research and Technical Skills
Lesley Mathews Griner possesses extensive technical skills in various laboratory techniques. She is proficient in quantitative high throughput screening (qHTS), matrix combination compound screening, and protein purification. Her expertise extends to histology, immunohistochemistry (IHC), and immunocytochemistry (ICC). She has experience with microarray technologies, particularly Agilent platforms, and is skilled in liquid handling and robotics for laboratory automation.
Mentoring and Leadership Experience
Lesley Mathews Griner has demonstrated a commitment to mentoring and training the next generation of scientists. She served on the Board of Directors and as Co-Chair of the Mentoring Committee for the Association for Women in Science from 2014 to 2016. This role reflects her dedication to fostering professional development and supporting women in the scientific community.