Yinghui Guan
About Yinghui Guan
Yinghui Guan serves as the Associate Director of Clinical Biomarkers and PK at IGM Biosciences, Inc., where he has worked since 2022. He holds a PhD from the University of British Columbia and has extensive experience in oncology biomarker development, having previously worked at Genentech for over a decade.
Work at IGM Biosciences
Yinghui Guan serves as the Associate Director of Clinical Biomarkers and Pharmacokinetics (PK) at IGM Biosciences, Inc., a position he has held since 2022. In this role, he focuses on advancing clinical biomarker strategies and pharmacokinetic assessments to support drug development initiatives. His expertise contributes to the identification and validation of biomarkers that are crucial for the evaluation of therapeutic efficacy.
Education and Expertise
Yinghui Guan earned his PhD in Malignant Stem Cells in Acute Myeloid Leukemia from the University of British Columbia, where he studied from 1996 to 2002. He also holds a Master of Science in Biochemistry and Molecular Biology and a Bachelor of Science in Ecology and Environmental Biology, both from Peking University. His educational background provides a strong foundation in molecular and cellular biology, with a focus on cancer research.
Background in Oncology Biomarker Development
Prior to his current role, Yinghui Guan worked at Genentech for a total of ten years, where he held various positions, including Oncology Biomarker Study Lead and Senior Principal Scientific Researcher in Oncology Biomarker Development. His work involved leading projects that focused on the development of biomarkers for oncology, contributing to significant advancements in cancer research.
Research Experience and Contributions
Yinghui Guan has over ten years of hands-on laboratory experience in molecular and cellular biology, gained through positions at prestigious research institutions. His research includes the discovery and application for a patent related to a gene causing ovarian cancer. He specializes in cell signaling pathways, target validation, and biomarker development, employing advanced technologies such as RNA interference and small hairpin RNA.
Technical Skills and Methodologies
Yinghui Guan possesses a range of technical skills relevant to cancer research. He is proficient in developing cell-based assays, including high-throughput cell immunostaining and imaging. His expertise extends to flow cytometry, cancer mouse models, and the production of hybridoma and monoclonal antibodies. He is also experienced in cloning, mammalian cell culture, and expression and copy number microarrays.