Dennis Earle Ms, MBA
About Dennis Earle Ms, MBA
Dennis Earle is a Senior Director of Clinical Science at Mirati Therapeutics, with extensive experience in drug development and regulatory affairs. He has held leadership positions at several pharmaceutical companies, including Bristol Myers Squibb and Actinium Pharmaceuticals, and has a strong academic background in pharmacology and business administration.
Work at Mirati Therapeutics
Dennis Earle serves as the Senior Director of Clinical Science at Mirati Therapeutics, a position he has held since 2021. In this role, he is responsible for overseeing clinical development strategies and ensuring the successful advancement of clinical programs. His expertise in clinical science contributes to the company's mission of developing innovative therapies for cancer treatment. Mirati Therapeutics is known for its focus on targeted therapies and precision medicine.
Previous Experience in Clinical Development
Prior to his current role, Dennis Earle held several significant positions in the pharmaceutical industry. He worked at Bristol Myers Squibb as Team Leader in Clinical Science for Late Stage Oncology Clinical Development from 2015 to 2021. He also served as Executive Director of Medical Affairs and Real-World Evidence at Repare Therapeutics for a brief period in 2021. His experience includes leadership roles at Actinium Pharmaceuticals, Intercept Pharmaceuticals, Onconova Therapeutics, and Palatin Technologies, where he contributed to various aspects of clinical operations and development.
Education and Expertise
Dennis Earle holds a Master of Science in Pharmacology from The Johns Hopkins University. He also earned a Master of Business Administration with a focus on Pharmaceutical Marketing and Management from Saint Joseph's University. His undergraduate studies include a Bachelor of Arts in Biochemistry and English from Rutgers University. This educational background supports his extensive expertise in clinical development, regulatory strategies, and drug approval processes.
Regulatory Approval Experience
Dennis Earle has extensive experience in preparing and submitting applications for New Drug Applications (NDA), Marketing Authorization Applications (MAA), and Biologics License Applications (BLA). His proven ability to navigate the regulatory landscape is critical in advancing clinical programs and achieving product approvals. This experience spans various roles throughout his career, highlighting his proficiency in clinical and regulatory strategies.
International Drug Development Background
Dennis Earle possesses broad and deep international drug development experience, covering the entire spectrum from Investigational New Drug (IND) candidate nomination to commercial product launch. His comprehensive understanding of the drug development process enables him to effectively manage clinical programs and align them with regulatory requirements. This background enhances his capability to lead teams in achieving successful clinical outcomes.