Thomas Hooker
About Thomas Hooker
Thomas Hooker is a Senior Director of Analytical Development at Mirati Therapeutics, with extensive experience in the pharmaceutical industry, including roles at notable companies such as Gilead Sciences and Bristol-Myers Squibb. He holds a Ph.D. in Analytical Chemistry from the University of North Carolina at Chapel Hill and has a strong background in chromatographic techniques and method development.
Current Role at Mirati Therapeutics
Thomas Hooker serves as the Senior Director of Analytical Development at Mirati Therapeutics, a position he has held since 2021. In this role, he oversees analytical development processes and ensures compliance with regulatory standards. His responsibilities include method development and validation for small molecule GMP drug products, contributing to the advancement of therapeutic solutions within the organization.
Previous Experience in the Pharmaceutical Industry
Thomas Hooker has extensive experience in the pharmaceutical sector, having held various positions prior to his current role. He worked as the Senior Director of Analytical and QC at Odonate Therapeutics from 2018 to 2021. Before that, he was a Senior Research Scientist II/Associate Director at Gilead Sciences from 2012 to 2016. His career also includes roles at Bristol-Myers Squibb, Dart NeuroScience LLC, and Biotie Therapies/Acorda Therapeutics, where he developed a strong foundation in analytical chemistry.
Educational Background in Chemistry
Thomas Hooker earned his Ph.D. in Analytical Chemistry from the University of North Carolina at Chapel Hill, where he studied from 1992 to 1997. He also holds a Bachelor of Science degree in Chemistry from Villanova University, completed from 1988 to 1992. His educational background has equipped him with a deep understanding of analytical techniques and methodologies relevant to the pharmaceutical industry.
Expertise in Analytical Techniques
Thomas Hooker possesses expertise in various analytical techniques essential for pharmaceutical development. He is skilled in chromatographic methods, including Liquid Chromatography (HPLC and uHPLC), Capillary Electrophoresis (CE), and Gas Chromatography (GC). His experience includes analyzing potentially mutagenic and genotoxic impurities in pharmaceutical products, as well as authoring Chemistry, Manufacturing, and Controls (CMC) sections for Investigational New Drug (IND) and New Drug Application (NDA) submissions.
Leadership in Contract Research and Manufacturing
Throughout his career, Thomas Hooker has demonstrated leadership in overseeing Contract Research Organizations (CRO) and Contract Manufacturing Organizations (CMO) within the pharmaceutical industry. His role in managing these partnerships has been critical in ensuring the successful development and validation of analytical methods, as well as maintaining compliance with industry regulations.