Istvan Botos
About Istvan Botos
Istvan Botos is a Staff Scientist at the National Institutes of Health, specializing in the structural basis of TLR3 signaling with dsRNA. He has extensive experience in structural biology and system administration within research environments.
Work at National Institutes of Health
Istvan Botos has been employed as a Staff Scientist at the National Institutes of Health (NIH) within the National Institute of Diabetes and Digestive and Kidney Diseases since 2005. In this role, he focuses on investigating the structural basis of Toll-like receptor 3 (TLR3) signaling with double-stranded RNA (dsRNA). His responsibilities also include setting up and maintaining web servers and research pages for the Laboratory of Molecular Biology crystallography groups, as well as planning and implementing new hardware and software solutions for structural research.
Previous Experience at National Cancer Institute
Prior to his current position, Istvan Botos worked as a Postdoctoral Researcher at the National Cancer Institute (NCI) from 2000 to 2005. During this five-year tenure, he contributed to various research projects in the field of cancer biology. His experience at NCI provided him with a strong foundation in research methodologies and collaborative scientific work.
Education and Expertise
Istvan Botos earned his Ph.D. in Biochemistry from Texas A&M University, where he studied from 1992 to 2000. His doctoral research laid the groundwork for his expertise in structural biology and biochemistry. He also briefly served as a Postdoctoral Research Fellow at Texas A&M University for one month in 2000, further enhancing his research skills and knowledge in the field.
Research Contributions
Botos conducts structural studies on the lipopolysaccharide transporter membrane protein complex known as LPTDE. His work involves detailed investigations into the molecular mechanisms of protein complexes, contributing to the understanding of cellular processes. Additionally, he is responsible for the system administration of servers and workstations for the Laboratory of Molecular Biology crystallography groups, ensuring the integrity and availability of research data through daily backups and archives.