Manu Thomas Kalathottukaren

Scientist I (Functional Biomaterials) @ Notch Therapeutics

About Manu Thomas Kalathottukaren

Manu Thomas Kalathottukaren is a Scientist I specializing in Functional Biomaterials at Notch Therapeutics in Vancouver, Canada. He has extensive experience in biomaterial applications, protease activity assays, and the interaction of nanomaterials with biological systems.

Current Role at Notch Therapeutics

Manu Thomas Kalathottukaren serves as Scientist I in Functional Biomaterials at Notch Therapeutics since 2020. In this role, he focuses on the development and application of biomaterials for therapeutic purposes. His work involves utilizing advanced techniques to enhance the functionality and efficacy of biomaterials in medical applications.

Previous Experience at Kardium Inc.

Kalathottukaren worked as a Research Scientist at Kardium Inc. from 2018 to 2020 in the Vancouver, Canada Area. During his tenure, he developed expertise in the synthesis of hyperbranched polyglycerols and their conjugation with fluorophores. This work contributed to advancements in biomaterial applications, particularly in the context of medical devices.

Postdoctoral Research at The University of British Columbia

From 2017 to 2018, Kalathottukaren was a Postdoctoral Research Fellow at The University of British Columbia. His research during this period involved studying various aspects of biomaterials and their interactions within biological systems. This role built upon his extensive academic background and research experience.

Educational Background

Kalathottukaren earned his Doctor of Philosophy (PhD) in Pathology and Laboratory Medicine from The University of British Columbia, completing his studies from 2011 to 2017. Prior to this, he obtained a Master's Degree in Medicinal and Pharmaceutical Chemistry from The Tamil Nadu Dr. M.G.R. Medical University in Chennai from 2006 to 2008. He also holds a Bachelor's Degree in Pharmaceutical Sciences from the same university, completed from 2000 to 2004.

Research Skills and Expertise

Kalathottukaren possesses a strong skill set in biophysical techniques, including UV, CD, and fluorescence spectroscopy, to analyze the interactions of nanomaterials with blood proteins. He has experience in conducting thermodynamic studies using isothermal titration calorimetry to screen drug libraries and elucidate mechanisms of action. His background includes knowledge of blood coagulation disorders such as thrombosis and hemophilia, as well as histopathological analysis of organs.

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