PipeBio
PipeBio, based in Aarhus, Denmark, is a SaaS bioinformatics company that provides a platform for analyzing NGS and Sanger sequences, focusing on antibody, peptide screening, and drug development in the healthcare therapeutics industry.
Services
PipeBio provides a SaaS bioinformatics platform for the healthcare industry, focusing specifically on therapeutics. The platform offers a wide range of features including annotation and identification of sequence liabilities, clustering and comparing samples, and visualization with interactive charts. Scientists and bioinformaticians can automate workflows for identifying candidate sequences from large-scale NGS antibody repertoires, hybridoma sequencing, and clonal expansion in biopanning experiments. The platform allows for the storage of antibody sequences in a central database with associated metadata and provides tools for antibody engineering, including editing sequences at the nucleotide or protein level.
Products
The core product offered by PipeBio is its bioinformatics cloud for antibody, peptide screening, and drug development. The platform integrates with ELN, LIMS, and internal tools through a REST API, enabling the creation of automated pipelines. Key features include standardized sequence analysis pipelines, the ability to compare sequences from new experiments with sequences found in the database or public databases, and tools for antibody engineering. With a highly visual software design, users can overlay and filter information from different sources across their organization to drive insights and improve drug discovery processes.
Technology
PipeBio leverages AI-powered drug discovery and machine learning technologies to empower scientists to manage and analyze extensive DNA sequencing data without needing specialized bioinformatics expertise. The platform supports sequence analysis for BCR, TCR, VHH, scFv, or peptide sequences and includes features like calculating protein properties, optimizing degenerate codons for synthesis, and analyzing the hydrophobicity of sequences. Functional assay data and metadata can be associated with sequences, and users can conduct comprehensive analyses of protein properties, such as ELISA and transcriptomics.
Location and Team
PipeBio operates from Aarhus, Denmark, but also offers remote work options, making it a fully remote-friendly company. The team consists of three members, allowing for a highly focused and collaborative work environment. The company's reach extends across Denmark, Europe, and beyond, with its services designed for global accessibility. Participating in the Y Combinator W21 batch highlights its innovative approach and presence in the competitive startup ecosystem.
Publications
PipeBio actively publishes articles on various important topics in the healthcare and therapeutics field. Recent publications cover subjects such as predicting antibody structure and developability, antibody conferences to attend, and the development of next-generation vaccines. By sharing insights and research findings, PipeBio contributes to the broader scientific community and keeps its users informed about the latest advancements and trends within the industry.