Friedrich Fauser
About Friedrich Fauser
Friedrich Fauser is a Senior Scientist at Sangamo Therapeutics, specializing in genome engineering and gene editing technologies. He has a strong academic background with a Ph.D. from Karlsruhe Institute of Technology and has contributed to significant research in the field, including the development of tools for treating genetic diseases.
Work at Sangamo Therapeutics
Friedrich Fauser joined Sangamo Therapeutics in 2017 and has been serving as a Senior Scientist since 2021. His work focuses on developing innovative tools aimed at transforming the lives of patients with serious genetic diseases. Fauser has utilized a genome-saturating Chlamydomonas mutant collection along with high-throughput tools to investigate DNA recombination mechanisms. He has contributed to the systematic development of reprogrammed modular integrases for genomic integration, enhancing gene editing specificity, and diversifying the structure of zinc finger nucleases for high-precision genome editing.
Education and Expertise
Friedrich Fauser studied at the Karlsruhe Institute of Technology, where he earned a Diploma in Biology from 2006 to 2011. He continued his education at the same institution, achieving a Dr. rer. nat. (PhD) in Biology from 2011 to 2014. His academic background includes developing site-specific genome engineering techniques for plants during his Ph.D. studies. Fauser's expertise encompasses CRISPR/Cas systems, DNA double-strand break inducing agents, and various gene editing technologies.
Background
Friedrich Fauser's research background includes significant work in the Jonikas lab at the Carnegie Institution for Science, where he explored the rapid engineering of photosynthetic organisms. During his Ph.D. research, he focused on transferring the CRISPR/Cas system to Arabidopsis and worked with other DNA double-strand break inducing agents such as ZFN, TALENs, and Meganucleases. His postdoctoral research was supported by a fellowship from the German Academic Exchange Service (DAAD).
Achievements
Friedrich Fauser has co-authored multiple scientific publications related to zinc finger technology and its applications. His contributions include research on compact zinc finger architecture for base editing in human cells and allele-selective transcriptional repression aimed at treating Huntington's disease. He has also been involved in research focused on enhancing gene editing specificity by attenuating DNA cleavage kinetics, showcasing his commitment to advancing gene editing methodologies.