S. Sianna Castillo
About S. Sianna Castillo
S. Sianna Castillo is a Senior Director at Sangamo Therapeutics, specializing in CMC regulatory strategies for cellular gene therapy and gene editing products. With extensive experience in regulatory affairs at BioMarin Pharmaceutical Inc. and a strong academic background in nutrition and molecular sciences, she effectively leads regulatory interactions with health authorities.
Current Role at Sangamo Therapeutics
S. Sianna Castillo serves as the Senior Director at Sangamo Therapeutics, Inc. since 2021. In this role, she focuses on developing and implementing CMC regulatory strategies for cellular gene therapy and gene editing products. She ensures compliance with regulatory guidelines and leads interactions with health authorities. Castillo is responsible for preparing briefing packages and conducting meetings to address CMC issues effectively.
Previous Experience at BioMarin Pharmaceutical Inc.
Castillo held multiple positions at BioMarin Pharmaceutical Inc. from 2007 to 2021. She began as a Scientist II, advancing to Associate Director of Regulatory Affairs, CMC, and later served as Director of Regulatory Affairs for the CMC Group. During her tenure, she developed innovative regulatory strategies for gene therapy products and facilitated negotiations with regulatory agencies to resolve CMC issues.
Education and Expertise
S. Sianna Castillo holds a PhD in Biochemical and Molecular Nutrition from Purdue University, earned between 1996 and 2000. She also obtained a Master of Science in Biochemical Nutrition from the University of Kentucky and a Bachelor of Science in Nutrition and Food Science from the University of California, Berkeley. Her educational background supports her expertise in regulatory affairs and CMC strategies in the biotechnology sector.
Postdoctoral Experience
Castillo has extensive postdoctoral experience, having worked as a Post-doctoral Fellow at the National Institutes of Health (NIH) from 2000 to 2004 and as a Post-doctoral Scholar at UC Davis from 2004 to 2007. This experience contributed to her foundational knowledge in biochemical nutrition and regulatory science, which she applies in her current role.
Coaching and Mentorship
In her current position at Sangamo Therapeutics, Castillo actively coaches and mentors members of the CMC Regulatory team. She focuses on developing effective strategies and fostering a collaborative environment to enhance team performance and regulatory compliance in the development of gene therapy products.