Yiling Bi
About Yiling Bi
Yiling Bi is a Scientist II specializing in Analytical Method Development at Sangamo Therapeutics, where she focuses on gene and cell therapy drug products. With a PhD in Medicinal and Pharmaceutical Chemistry from the University of Utah, she has extensive experience in method development and regulatory submissions.
Current Role at Sangamo Therapeutics
Yiling Bi currently holds the position of Scientist II in Analytical Method Development at Sangamo Therapeutics, Inc. since 2020. In this role, Bi manages outsourcing to Contract Research Organizations (CROs) and Clinical Trial Laboratories (CTLs) for feasibility studies, method development, data review, and technology transfer related to gene and cell therapy drug products. Bi has developed and optimized analytical methods specifically for biologics programs and has contributed to the preparation of Chemistry, Manufacturing, and Controls (CMC) regulatory submissions.
Previous Experience in Biotech
Prior to joining Sangamo Therapeutics, Yiling Bi worked at several biotechnology companies. Bi served as Scientist I in Analytical and Bioassay Development at Five Prime Therapeutics, Inc. for three months in 2019. Following that, Bi worked at Hengenix Biotech, Inc. as Scientist I in Analytical and Process Development for ten months from 2019 to 2020. In these roles, Bi focused on developing analytical methods and supporting various drug development processes.
Internship Experience at Bosch USA
In 2019, Yiling Bi completed a five-month internship at Bosch USA as a Biochemistry Intern. This experience provided Bi with practical exposure to the application of biochemistry in a corporate setting, contributing to the development of skills relevant to the field of analytical method development.
Education and Academic Background
Yiling Bi earned a Doctor of Philosophy (PhD) in Medicinal and Pharmaceutical Chemistry from the University of Utah, where Bi studied from 2013 to 2019. Prior to this, Bi obtained a Bachelor of Science (BS) in Pharmacy from Shandong University, completing the degree from 2009 to 2013. During the academic tenure, Bi also served as a Graduate Research Assistant at the University of Utah for five years, contributing to research efforts in the field.
Technical Expertise in Analytical Methods
Yiling Bi has established a platform for AAV viral vector characterization assays utilizing LC-MS and LC-MS/MS techniques. Bi has designed and supervised the development of High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) methods for assessing AAV vector and genome purity and impurity. This technical expertise supports Bi's contributions to the field of gene and cell therapy.