Hyun Gyung Jang, PhD
About Hyun Gyung Jang, PhD
Hyun Gyung Jang, PhD, is a Principal Scientist at Wave Life Sciences, where he provides DMPK support for antisense oligonucleotides related to genetic disease therapeutics. He has extensive experience in managing ADME studies and leads DMPK efforts for projects targeting conditions such as Huntington Disease and Duchenne Muscular Dystrophy.
Work at Wave Life Sciences
Hyun Gyung Jang, PhD, has been serving as a Principal Scientist at Wave Life Sciences since 2020. In this role, he provides Drug Metabolism and Pharmacokinetics (DMPK) support specifically for antisense oligonucleotides aimed at treating genetic diseases. His work involves leading DMPK efforts for projects targeting conditions such as Huntington Disease, Duchenne Muscular Dystrophy, and various hepatic conditions. He collaborates closely with research scientists and toxicologists, acting as a liaison between discovery and development teams to ensure effective communication and project progression.
Education and Expertise
Hyun Gyung Jang holds a PhD in Pharmaceutical Chemistry from The Hebrew University of Jerusalem, where he studied from 1995 to 2000. Prior to this, he completed a Bachelor of Science in Chemistry and a Master of Science in Biochemistry at Konkuk University, studying from 1994 to 1999. His educational background provides a strong foundation in the principles of chemistry and biochemistry, which he applies in his current research and development work in the pharmaceutical industry.
Regulatory Document Authorship
Throughout his career, Hyun Gyung Jang has authored various regulatory documents essential for drug development. These include New Drug Applications (NDA), Investigational New Drug applications (IND), pre-Clinical Trial Applications (pre-CTA BB), and Investigational Medicinal Product Dossiers (IMPD). His expertise in regulatory documentation supports the advancement of therapeutic projects within the pharmaceutical sector.
ADME Studies Management
In his role at Wave Life Sciences, Hyun Gyung Jang manages comprehensive Absorption, Distribution, Metabolism, and Excretion (ADME) studies. These studies encompass in vitro and in vivo metabolism, drug-drug interactions, and plasma protein binding. His management of these studies is critical for understanding the pharmacokinetics of drug candidates and ensuring their safety and efficacy in clinical applications.