Mark Plummer
About Mark Plummer
Mark Plummer is an Associate Research Scientist with extensive experience in medicinal chemistry, particularly in drug discovery and development. He has worked at notable institutions such as Pfizer and Yale University, contributing to advancements in structure-activity relationships, pharmacokinetics, and synthetic chemistry.
Work at Yale University
Mark Plummer has been employed at Yale University since 2012. He initially served as a Research Associate for one year before transitioning to his current role as an Associate Research Scientist. He has been part of the Yale Center for Molecular Discovery for over a decade, contributing to various research initiatives. In addition to his role in the Center for Molecular Discovery, he is also involved in the Department of Molecular Cellular and Developmental Biology. His work focuses on drug discovery and optimization, leveraging his extensive background in medicinal chemistry.
Education and Expertise
Mark Plummer holds a Bachelor of Arts in Chemistry from Colby College, which he completed from 1978 to 1982. He pursued further studies at Rensselaer Polytechnic Institute, earning a PhD in Organic Chemistry between 1982 and 1986. He then conducted postdoctoral research in Organic Synthesis at Stanford University from 1988 to 1990. His educational background has equipped him with a strong foundation in medicinal chemistry, structure-activity relationships, and synthetic chemistry.
Previous Experience at Pfizer
Before joining Yale University, Mark Plummer worked at Pfizer as an Associate Research Fellow from 2001 to 2011. During his tenure, he made significant contributions to the fields of pharmacokinetics and synthetic chemistry. His work involved leading multidisciplinary drug discovery teams and engaging with senior leadership to establish project goals and timelines. He focused on therapeutic areas including antibacterials, inflammation, pain, and cardiovascular diseases.
Current Role at Nalas Engineering Services, Inc.
Since 2020, Mark Plummer has been employed as Scientist V at Nalas Engineering Services, Inc. located in Centerbrook, CT. In this role, he applies his expertise in drug discovery and optimization to support the company's objectives. His extensive experience in structure-based drug design and medicinal chemistry informs his contributions to ongoing projects.
Research Contributions and Achievements
Mark Plummer has made notable contributions in the areas of structure-activity relationships, pharmacokinetics, and synthetic chemistry routes. He has successfully carried projects from concept through various stages of drug development, including screening, hit to lead evaluation, and lead optimization. His strong track record includes optimizing druggable properties to produce quality clinical candidates, demonstrating his commitment to advancing drug discovery efforts.