AmberGen

AmberGen

AmberGen specializes in advanced spatial biology research products, offering a range of Miralys technology-based probes, panels, and kits that enhance mass spectrometry imaging capabilities.

Products

AmberGen offers a range of Miralys products designed for spatial biology research. This product line includes probes, panels, and kits specifically tailored to enhance mass spectrometry imaging capabilities. The Miralys technology enables imaging of up to 150+ intact protein biomarkers within approximately 45 minutes. Additionally, AmberGen provides dual-labeled antibody probes, combining mass-tags and fluorophores for multimodal imaging purposes. Their product portfolio also features Miralys Antibody Conjugation kits for custom antibody labeling with photocleavable mass-tag codes.

Technology

AmberGen’s proprietary Miralys Photocleavable Mass-Tag Imaging technology significantly advances mass spectrometry imaging. This technology facilitates high-plex, multiomic, and multimodal spatial imaging of intact proteins and unlabeled small molecules in tissue samples. It supports the imaging of various biological molecules, including small molecules, lipids, glycans, extracellular matrix components, and intact proteins on a unified panel using mass spectrometry imaging.

Collaborations

AmberGen collaborates with Bruker Corporation to enhance spatial biology imaging reagents for MALDI-Immunohistochemistry (MALDI-IHC). This partnership leverages the strengths of both companies to provide advanced solutions for spatial imaging and mass spectrometry applications. In 2022, AmberGen received a minority investment from Bruker, further solidifying their collaborative efforts in the spatial biology sector.

Miralys Technology Applications

The Miralys technology developed by AmberGen is pivotal for multiomic imaging applications within the field of spatial biology. It allows for the concurrent analysis of small molecules, lipids, glycans, extracellular matrix components, and intact proteins. This capability provides researchers with comprehensive insights into the molecular composition of biological tissues, supporting high-resolution spatial imaging and advanced biomarker discovery.

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