Cell Microsystems

Cell Microsystems

Cell Microsystems offers advanced platforms like the CellRaft AIR System and BioFlux system, which enhance cell viability and emulate in vivo conditions for various research applications.

Cell Microsystems Services

Cell Microsystems provides advanced biotechnological platforms designed to enhance cell viability and research accuracy. The primary offerings include the CellRaft AIR System and the BioFlux system. The CellRaft AIR System maintains cells in an unperturbed state, leading to higher viability, superior clonal outgrowth, and the ability to generate 10-50 times more viable monoclonal colonies than traditional methods. The BioFlux system introduces physiological shear flow to research and drug discovery experiments, creating in vivo conditions for accurate study and analysis.

Cell Microsystems Product: CellRaft AIR System

The CellRaft AIR System is an integrated platform that relies on proprietary technology to maintain cells in an unperturbed state. This results in improved cell viability and the generation of highly proliferative colonies. The system supports a variety of applications including cell line development, CRISPR gene editing, stem cell culture, organoid development, and single-cell genomics. It features powerful label-free brightfield and fluorescence analysis software for cell identification, and can automatically isolate cells or colonies for downstream analysis or clonal expansion. It also creates a complete image-based record of all clones to support regulatory submissions.

Cell Microsystems Product: BioFlux System

The BioFlux system allows for the introduction of physiological shear flow to experiments, effectively emulating in vivo conditions. It is ideal for drug discovery, research on live cell transmigration, and studying the effects of COVID-19 and its vaccines on platelet function, acting as an 'artery on a chip.' The system supports various applications such as bacterial mutant screens, quantitative wounding assays, and the analysis of bacterial and fungal biofilms, including lung biofilms in cystic fibrosis patients. It provides the ability to conduct time-lapse microscopy to study dynamic cell processes and post-experiment image analysis for precise data.

Cell Microsystems Technology Applications

Cell Microsystems' technology is utilized for several innovative applications. The CellRaft AIR System supports cell line development, CRISPR gene editing, stem cell culture, organoid development, and single-cell genomics. It also provides comprehensive image-based records for regulatory compliance. The BioFlux system is used to replicate in vivo conditions by introducing physiological shear flow, enabling studies on leukocyte transmigration, bacterial and fungal biofilms, and the effects of COVID-19 on platelet function. It generates consistent wounds for quantitative assays and allows for precise analysis of cell migration and biofilm formation under physiologically relevant conditions.

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