Emulate
Emulate offers a range of Organ-Chip models and comprehensive support to enable insights into human biology through their Human Emulation System.
Services
Emulate offers a comprehensive range of services designed to support Organ-Chip experiments. These include standard and custom services, virtual installation guidance, and extensive support to help new users with setup. The company also provides in-depth scientific training and validated protocols for Organ-Chip culture and experimental analysis, ensuring researchers can effectively utilize their products for accurate biological modeling.
Products
Emulate's product lineup features a variety of Organ-Chip models, such as the Brain-Chip, Colon Intestine-Chip, Duodenum Intestine-Chip, Kidney-Chip, Liver-Chip, and Lung-Chip. These chips are supplied in kits that include necessary reagents and qualified human cells. The Human Emulation System integrates instruments, consumables, and software, including the Zoë Culture Module, to enable precise modeling of human biology. Additionally, Emulate offers a CAR T workflow to simulate CAR T-cell therapy.
Liver-Chip
The Liver-Chip from Emulate combines four types of human cells in a dynamic microenvironment that supports in vivo-like gene expression, functionality, and physiology. This chip serves as a validated preclinical human liver model that accurately recapitulates the physiological functions of the human liver, enabling researchers to study liver functionality and the effects of various treatments in a controlled setting.
Colon Intestine-Chip
Emulate's Colon Intestine-Chip integrates pre-qualified biopsy-derived primary human organoids and colonic endothelial cells, incorporating mechanical forces to emulate in vivo physiology. This chip can be utilized to study the efficacy and mechanisms of drug candidates that target the recruitment of PBMCs from the vasculature to the gut luminal tissue, providing insights into gut-related diseases and potential treatments.
Brain-Chip
The Brain-Chip offered by Emulate includes five types of human cells: neurons, astrocytes, pericytes, microglia, and brain microvascular endothelial-like cells. This composition enables intricate modeling of the human brain, facilitating research into neuronal interactions, blood-brain barrier functions, and neurodegenerative diseases. The Brain-Chip aids in understanding brain physiology and the effects of various therapeutic interventions.