EpiVax
EpiVax is a company specializing in computational immunology tools and services, including immunogenicity assessment, deimmunization, and vaccine design.
Services
EpiVax offers a range of services tailored to the fields of computational immunology and vaccine design. Their core services include immunogenicity assessment, deimmunization, and vaccine design. They also provide laboratory services such as HLA binding assays and T cell assays. Additionally, EpiVax provides consulting services through their Trusted Expert Advice (TEA) program, and offers specific services like PANDA for immunogenicity screening of generic peptide drugs and ISPRI-HCP for immunogenicity screening of host cell proteins.
Products
EpiVax has developed several proprietary tools and toolkits to support their services. Their ISPRI toolkit is a comprehensive in silico toolkit for immunogenicity screening and optimization, including tools like EpiMatrix, ClustiMer, JanusMatrix, and OptiMatrix. The iVAX toolkit is used specifically for designing epitope-driven vaccines. EpiCC is another proprietary tool for assessing the relatedness of T cell epitopes in vaccine sequences. Additionally, Tregitope is a tool designed for immunomodulation by activating regulatory T cells.
Innovative Approaches in Vaccine Design
EpiVax employs a 'Gene-to-Vaccine' design approach for the development of biodefense vaccines. This methodology leverages computational tools to streamline the process from genetic sequencing to vaccine creation. Their iVAX toolkit further supports epitope-driven vaccine design, which focuses on identifying specific protein fragments to generate a targeted immune response.
Location
EpiVax operates out of a corporate office and laboratory located in Providence, Rhode Island. This centralized location supports both their business operations and research activities, enabling close coordination between their computational scientists and laboratory personnel.
Community Engagement
EpiVax actively supports local and international non-profits and encourages employee volunteerism. This commitment to community engagement underscores the company’s dedication to corporate social responsibility and fosters a culture of giving back among its employees.