Harmonic Discovery

Harmonic Discovery, based in New York with a remote team, specializes in developing multi-specific drugs for diseases like cancer and neurodegeneration by leveraging a computational-experimental platform and partnerships with biotech and pharmaceutical companies.

Services

Harmonic Discovery focuses on therapeutics within the human kinome, targeting a family of 500 proteins linked to diseases like cancer, autoimmunity, and neurodegeneration. The company leverages genetic screening, biochemical assays, and bioinformatics to predict targets that work synergistically when inhibited together. They also identify anti-targets that cause toxicity when inhibited. Their approach incorporates computational and experimental platforms to design multi-specific drugs, using generative machine learning, chemical informatics, and medicinal chemistry. This method aims to optimize the binding profile, selectivity, and ADME properties of compounds.

Founders

Harmonic Discovery was part of the Y Combinator S21 batch. This accelerator has a history of supporting innovative startups, particularly in the tech and healthcare industries. While specific names of the founders are not provided, their involvement in Y Combinator indicates a strong foundation in entrepreneurship and innovation.

Products

Harmonic Discovery is developing a new generation of therapeutics that target multiple disease-causing proteins simultaneously. The company's products are focused on treating conditions associated with the human kinome, particularly diseases such as cancer, autoimmunity, and neurodegeneration. Using a computational-experimental platform, they employ generative machine learning and chemical informatics to design these multi-specific drugs, continually optimizing them for efficacy and safety.

History

Harmonic Discovery became part of the healthcare industry with a sub-industry focus on Drug Discovery and Delivery. Established within the Y Combinator S21 batch, they have since grown to a team size of 8. The company has offices in New York, NY, USA, but also provides remote work options. Their approach combines cutting-edge technology in generative machine learning and bioinformatics with traditional biochemical assays to create innovative therapeutics.

Employee Benefits

Harmonic Discovery offers competitive salary and equity compensation packages. Employees benefit from paid time off, holiday bonuses, and flexible working environments. The company also organizes company off-sites to enhance team cohesion. Comprehensive medical benefits and a 401(k) plan are also part of the employee benefits package, ensuring a well-rounded support system for their workforce.

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