OnLume - Bringing Fluorescence Image-Guided Surgery out of the Dark.
OnLume develops innovative fluorescence image-guided surgery technology that performs well in ambient light, providing high-resolution imaging and real-time procedural visualization to enhance surgical precision and patient outcomes.
Services
OnLume develops innovative medical imaging technology designed to advance surgical precision, optimize patient outcomes, and reduce morbidity and costs. The company's fluorescence-guided surgery (FGS) system provides high image quality with low fluorescent agent concentrations and is optimized for surgical workflows. This includes compatibility with ambient operating room lighting and a broad spectrum of targeted fluorescent drugs. OnLume's imaging system is used for fluorescence imaging of blood flow and tissue perfusion in vascular, gastrointestinal, organ transplant, plastic, reconstructive, and micro surgeries.
Products
The OnLume Imaging System is a state-of-the-art fluorescence-guided surgery device that operates effectively in ambient light while providing high-sensitivity imaging. It features an articulating imaging head and monitors, which offer ergonomic benefits to surgeons. The system uses FDA-approved indocyanine green (ICG) dye to visualize vascular patency and identify regions of poor blood flow. This advanced imaging technology allows for real-time visualization, enabling surgeons to perform precise procedures with improved outcomes.
Funding and Grants
OnLume has successfully completed a $7 million Series A financing round, which supports the commercial launch of its fluorescence image-guided surgery system. Additionally, the company has received significant financial support in the form of a $2 million grant from the National Cancer Institute. These funds are designated to advance the development of their novel fluorescence-guided surgery device. Such financial backing underscores the potential and readiness of OnLume's technology for widespread clinical use.
FDA Clearance and Clinical Trials
OnLume's fluorescence-guided surgery system has received US FDA 510(k) clearance for a variety of applications, including the imaging of blood flow and tissue perfusion before, during, and after surgeries. These include vascular, gastrointestinal, organ transplant, plastic, reconstructive, and micro surgeries. The system is actively involved in clinical trials, combining its imaging technology with novel nerve-targeting agents. Such regulatory approvals and ongoing research highlight OnLume's commitment to advancing surgical practices through innovative imaging solutions.
Awards and Collaborations
OnLume has been recognized for its groundbreaking technology with the 2020 Wisconsin Innovation Award. The company collaborates with top research universities, like the University of Wisconsin-Madison and the Morgridge Institute for Research. These partnerships have led to significant advancements and notable findings in fluorescence-guided surgery. OnLume is also working with developers of novel fluorescent agents, surgeons, and clinicians to continually enhance and expand the applications of their imaging system.