Repligen
Repligen specializes in bioprocessing applications and solutions, offering a wide range of products and technologies for the production of biologic drugs and advanced therapies.
Services
Repligen provides a wide range of bioprocessing applications and solutions designed for the production of biologic drugs. Their offerings include upstream and downstream filtration, chromatography, fluid management, cell culture supplements, ligands, and analytics. They also assist with process intensification, ATMP, ultrafiltration/diafiltration, continuous manufacturing, and fluid management.
Products
Repligen's product line includes technology breakthroughs and scalable hardware, software, and consumables for the development and manufacture of plasmid DNA, viral vectors, mRNA, and even cultivated meat. Notable products include single-use bioprocessing bags from FlexBiosys Inc., the TangenX® SC TFF device, and Metenova’s magnetic mixing technology. They also offer in-line GMP testing solutions with the CTech™ FlowVPX® spectrophotometer system, ready-to-use dialysis devices, and scalable dynamic dialysis systems. Chromatography products such as KRM Chromatography Systems and OPUS Pre-packed Columns are also part of their extensive inventory.
Technological Breakthroughs
Repligen focuses heavily on refining productivity and enhancing environmental and economic metrics. They offer scalable workflow solutions for new modalities including whole cells and cultivated meat. Their Gene Therapy Applications Center provides advanced applications expertise and gene therapy collaborations. They have developed solutions critical to mRNA and lipid nanoparticle production for vaccines and therapies.
Global Presence
Repligen has a substantial global footprint with major manufacturing sites located in the United States, Sweden, France, The Netherlands, Germany, and Estonia. They market their products through a direct commercial organization spanning the United States, Europe, and Asia, and through strategic partners and distributors in other selected markets. Their global Field Applications Specialists and industry experts offer hands-on process and implementation consultation.
Innovations and Acquisitions
Repligen has bolstered its portfolio through several key acquisitions, including FlexBiosys Inc., which enhances their single-use bioprocessing solutions, and Metenova, adding magnetic mixing technology to their offerings. They also introduced the TangenX® SC, known as the industry’s first holder-free, self-contained TFF device. These innovations underscore Repligen’s commitment to delivering new technologies and improving bioprocessing efficiencies.