ResistanceBio
ResistanceBio, formerly known as Viosera Therapeutics, is a healthcare company based in Menlo Park, CA, specializing in the development of custom cancer models that mimic clinical resistance evolution.
Company Overview
ResistanceBio, formerly known as Viosera Therapeutics, is a healthcare company specializing in the development of custom cancer models designed to mimic clinical resistance evolution. Headquartered at 980 O'Brien Drive, Menlo Park, CA, the company also operates in Overland, MO. With a team size of 15, ResistanceBio operates primarily within the United States and offers remote and partly remote work options.
Y-Combinator Involvement
ResistanceBio participated in the Winter 2019 batch of Y-Combinator, a renowned startup accelerator. This involvement provided the company with crucial mentorship, funding, and networking opportunities to further its research and development in therapeutics.
Cancer Model Development
ResistanceBio specializes in developing custom cancer models for drug and indication. These models are designed to capture clinical resistance mechanisms in a pre-clinical setting. The platform calibrates 240 unique conditions to match clinical endpoints and tunes the cellular environment based on known clinical outcomes and drug parameters.
Multiomic Analysis
The company employs multiomic analyses to identify resistance mechanisms. This includes genomic, transcriptomic, and proteomic insights. The analysis is conducted at single-cell resolution to optimize treatment strategies against resistance across diverse patient subpopulations.
Partnership Opportunities
ResistanceBio offers partnerships to develop custom cancer models tailored to specific drugs and indications. Through these partnerships, the company provides detailed insights into resistance mechanisms and patient subpopulations, preserving tumor heterogeneity and resistance mechanisms through extended drug exposure periods. Such collaborations are aimed at enhancing treatment strategies and clinical outcomes.
