TwinStrand Biosciences
TwinStrand Biosciences, based in Seattle, WA, offers Duplex Sequencing technology that significantly reduces sequencing error rates and provides products and services for genetic testing and analysis.
Services
TwinStrand Biosciences provides a range of specialized services including Nitrosamine Testing, Mutagenesis Testing, and custom services. These services are built around their proprietary Duplex Sequencing technology, which offers unparalleled accuracy in detecting genetic variants. The company also offers a cloud-based bioinformatics platform designed for error correction and analysis of sequencing data, enabling precise and reliable genetic analysis.
Products
TwinStrand Biosciences offers several specialized products, including the AML Assay and the Mutagenesis Assay. The AML MRD assay is particularly noteworthy for its sensitivity, capable of detecting mutations with a variant allele frequency as low as 0.01%. The company also provides sample preparation kits and software for automated data analysis and reporting, aimed at facilitating comprehensive and accurate genetic testing.
Duplex Sequencing Technology
The cornerstone of TwinStrand Biosciences' offerings is their Duplex Sequencing technology, which significantly reduces sequencing error rates from 1-in-100 to 1-in-10 million per nucleotide sequenced. This technology is essential for detecting rare genetic variants and has been validated through inter-laboratory studies, showing consistent results across different laboratories. It is employed in various research areas, including genetic toxicology and hematological cancers.
Collaborations and Industry Events
TwinStrand Biosciences collaborates with leaders in commercial, regulatory, and academic sectors on projects related to drug development, genetic toxicology, and basic biology. The company is active at major industry events such as the Society of Toxicology Annual Meeting and the American Society of Hematology Annual Meeting, showcasing their technology and sharing insights with the scientific community.
Location and Career Opportunities
Located in Seattle, WA, TwinStrand Biosciences is a rapidly growing company with a dedicated team. They offer career opportunities in various scientific and commercial roles, providing a dynamic and innovative work environment. The company is focused on advancing genetic analysis through cutting-edge technology and robust scientific research.